ethyl 4-oxopiperidine-3-carboxylate

ethyl 4-oxopiperidine-3-carboxylate - Names and Identifiers

Name	ethyl 4-oxopiperidine-3-carboxylate hydrochloride
Synonyms	TIMTEC-BB SBB003473 LABOTEST-BB LT00455216 3-CARBETHOXY-4-PIPERIDONE HCL ethyl 4-oxopiperidine-3-carboxylate ethyl-4-oxo-3-piperidine carboxylate 3-CARBETHOXY-4-PIPERIDONE HYDROCHLORIDE 3-Carbethoxy-4-Piperidone Hydrochloride (3S)-3-(ethoxycarbonyl)-4-oxopiperidinium (3R)-3-(ethoxycarbonyl)-4-oxopiperidinium Ethyl 4-piperidinecarboxylate hydrochloride ETHYL 4-PIPERIDONE-3-CARBOXYLATE HYDROCHLORIDE Ethyl 4-piperidone-3-carboxylate hydrochloride ethyl 4-oxopiperidine-3-carboxylate hydrochloride ETHYL 4-OXO-3-PIPERIDINECARBOXYLATE HYDROCHLORIDE 3-Carboethoxy-4-piperidone hydrochloride~Ethyl 4-oxo-piperidine-3-carboxylate hydrochloride
CAS	4644-61-5
EINECS	225-073-8
InChI	InChI=1/C8H13NO3/c1-2-12-8(11)6-5-9-4-3-7(6)10/h6,9H,2-5H2,1H3/p+1/t6-/m0/s1

ethyl 4-oxopiperidine-3-carboxylate - Physico-chemical Properties

Molecular Formula	C8H14ClNO3
Molar Mass	207.65
Melting Point	169-175 °C
Boling Point	265.5°C at 760 mmHg
Flash Point	114.4°C
Water Solubility	Soluble in water
Vapor Presure	0.00912mmHg at 25°C
Appearance	White powder
Color	White to Brown
BRN	3711279
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
MDL	MFCD00043267

ethyl 4-oxopiperidine-3-carboxylate - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29333990

ethyl 4-oxopiperidine-3-carboxylate - Reference Information

preparation

50.0g(0.20mol)
1-benzyl -3-ethoxycarbonyl -4-piperidone hydrochloride and 5.0g palladium carbon (Pd/C) were added to 500mL methanol, air was extracted, H2 was introduced, the temperature was raised to 40 ℃, and the reaction was 5h. Diatomite was added to the reaction solution for suction filtration, and the filtrate was evaporated to obtain solid. After drying in an oven at 40 ℃, 34.1g of solid was obtained with a yield of 98.4%.

Last Update：2024-04-09 20:52:54